Freshman guard Sharane Campbell scored 20 points and pulled down 12 rebounds to help Oklahoma hold off Oklahoma State 80-71 Saturday.
Oklahoma (15-6, 7-3 Big 12) won its third in a row, getting 16 points apiece from Jelena Cerina and Aaryn Ellenberg. Whitney Hand pulled down a career-high 13 rebounds for the Sooners.
Liz Donohoe and Tiffany Bias had 20 points to lead Oklahoma State (12-7, 4-6), which has lost three straight.
Oklahoma went ahead for good with 6:39 left on Kaylon Williams' jumper and then a Campbell three-pointer on an inbounds pass from Hand just 29 seconds later.
OSU won the first meeting 66-63 in Stillwater earlier this season.
Up next for the Sooners is a tough road game against No. 1 Baylor. The Cowgirls return to the court on Wednesday with a home game against Texas Tech.